Coronavirus disease 2019 (COVID-19) is an emerging global health emergency caused by the novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The global outbreak of SARS-CoV-2 infection has been declared a global pandemic by the World Health Organization (WHO). Accumulating evidence indicates that COVID-19 patients commonly develop neurological and psychiatric symptoms. Several case reports of COVID-19 with severe neurological complications reported NMDA-Receptor Encephalitis (NMDARE). NMDARE is an autoimmune disease, where the body generates antibodies against NMDA-Receptors in the brain. Most of the people with Anti-NMDAR Antibodies found in their sera do not have any symptoms. This may reflect the complexity of autoimmune diseases. Patients with severe COVID-19 infection have some elements of damage in the blood-brain barrier (BBB) due to the Cytokine storm. However, not only patients with severe COVID-19 have an inflammatory reaction, but patients with mild symptoms could also have inflammatory reactions. We assumed that the damage to the blood-brain barrier caused by the inflammatory reaction allows the antibodies to cross the BBB and causes neuro-psychiatric complications in COVID-19 patients. To further test this hypothesis, we have collaborated with the Department of Pharmacology at the University of Michigan Medical School to develop an assay to predict if COVID-19 patients will develop Neuropsychiatric symptoms based on the Anti-NMDAR antibodies levels in the serum and to further assess if there is an association between the circulating Anti-NMDAR antibodies and the severity of the neurological symptoms. Please learn more about this project
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A collection of educational opportunities that are tailored for undergraduate or medical interns.
In vitro study of axial pullout of pedicle screws.
Authors: Wu Z, Wang J, Nassar Sa, Dai K, Li M, Li Y.. Sha Ja, Yang X.
Presented in "the 10th national biomechanics conference and the 12th national biological rheology conference, chengdu, china, oct 11-15, 2012"
Use of Colloidal Oatmeal Soap Can Reduce Symptoms of Atopic Dermatitis Topical colloidal oatmeal (CO) can reduce local inflammation, itching, and a number of other indications, at low cost and with minimal side effects.
A self-contained, low-cost, lightweight, foldable/deployable or small-sized, multi-broadband antenna that has been invented and developed by world-renowned antenna scientist and R&D specialist Mohamed Sanad Ph.D., Faculty of Engineering at Cairo University.
Photocatalytic Reactor to Control Methicillin-resistant Staphylococcus aureus (MRSA) in a Hospital Environment.